Hosts Chile moved into the Copa America semi-finals as Mauricio Isla's
late winner knocked nine-man holders Uruguay out of the tournament.
Chile dominated a bruising contest, Eduardo Vargas and
Arturo Vidal both going close before Edinson Cavani was sent off for a
second yellow card.
Uruguay held out until the 82nd minute when Isla fired home from 16 yards.
In the closing moments of an ugly game Uruguay defender Jorge Fucile was red-carded for a second caution.
Juventus defender Mauricio Isla's goal was only his third for Chile
Chile will now face the winners of Friday's match between Bolivia and Peru (00:30 BST) for a place in the final.
Uruguay's tournament ended in disgrace in a stormy game that saw six yellow cards in addition to two reds at Estadio Nacional in Santiago.
The biggest talking point before Isla's winner was Cavani's first red card for Uruguay on his 76th appearance for his country.
Having been shown a yellow card for confronting a linesman, the 28-year-old Paris St-Germain forward was ordered off after TV pictures appeared to show Gonzalo Jara putting a hand on his buttocks.
Defender Jara theatrically fell to the ground in response to a raised hand from Cavani, whose father was involved in a fatal car crash in Uruguay this week.
He argued with the referee for several minutes before finally being persuaded to leave the pitch.
Uruguay self-destructed after falling behind, Fucile sent off for a second booking with two minutes remaining after bringing down Alexis Sanchez.
The match was then halted for several minutes after Uruguay's players surrounded the referee and linesman, and officials and players from both sides scuffled on the field.
Chile, who dominated the match with 80% possession, have never won the Copa America since its inception in 1916.
The other two quarter-finals feature Argentina against Colombia (00:30 BST) on Saturday and Brazil versus Paraguay on Sunday (00:30 BST).
Chile dominated possession throughout and had eight shots alone in the first half
The game descended into a bad tempered affair with scuffles between both sets of players breaking out at regular intervals
Edinson Cavani had never been sent off before in a Uruguay shirt
Lineup, Bookings (8) & Substitutions (5)
Chile
- 01 Bravo
- 04 Isla Booked
- 17 Medel
- 18 Jara
- 02 Mena
- 08 Vidal
- 21 DÃaz (Fernández - 71' )
- 10 ValdÃvia Booked (Pizarro - 85' )
- 20 Aránguiz
- 11 Vargas (Pinilla - 71' Booked )
- 07 Sánchez
Substitutes
- 03 Albornoz
- 05 Silva
- 06 Fuenzalida
- 09 Pinilla
- 12 Garcés
- 13 Rojas
- 14 Fernández
- 15 Beausejour
- 16 Pizarro
- 19 Gutiérrez
- 22 Henriquez Iturra
- 23 Herrera
Uruguay
- 01 Muslera
- 16 Maxi Pereira Booked
- 02 Giménez de Vargas
- 03 GodÃn
- 04 Fucile Dismissed after an earlier booking
- 05 Sánchez (RodrÃguez Portillo - 85' )
- 20 González
- 17 Arévalo Rios
- 07 RodrÃguez
- 09 Rolan (Hernández - 58' )
- 21 Cavani Dismissed after an earlier booking
Substitutes
- 08 Hernández
- 10 de Arrascaeta
- 11 Stuani
- 12 Muñoz
- 13 Silva
- 14 Lodeiro
- 15 Pereira
- 18 Corujo
- 19 Coates
- 22 RodrÃguez Portillo
- 23 Silva
Ref: Sandro Meira Ricci
Live Text Commentary
90:00 +10:07 Full time
90:00 +6:44 Attempt saved. Arturo Vidal (Chile) right footed shot from the centre of the box is saved in the bottom right corner. Assisted by David Pizarro.
90:00 +5:30 Foul by Mauricio Pinilla (Chile).
90:00 +5:30 Egidio Arévalo Rios (Uruguay) wins a free kick in the defensive half.
90:00 +4:20 Offside, Chile. Arturo Vidal tries a through ball, but Alexis Sánchez is caught offside.
90:00 +2:03 Delay over. They are ready to continue.
88:30 Delay in match (Chile) for fighting.
87:29 Dismissal
87:25 Foul by Jorge Fucile (Uruguay).
84:47 Substitution
83:34 Giménez (Uruguay) wins a free kick in the defensive half.
83:00 Jorge ValdÃvia (Chile) wins a free kick in the attacking half.
83:00 Foul by Egidio Arévalo Rios (Uruguay).
82:17 Gonzalo Jara (Chile) wins a free kick in the defensive half.
82:17 Foul by Abel Hernández (Uruguay).
Full Time Second Half ends, Chile 1, Uruguay 0.
90:00 +6:50 Corner, Chile. Conceded by Fernando Muslera. 90:00 +6:44 Attempt saved. Arturo Vidal (Chile) right footed shot from the centre of the box is saved in the bottom right corner. Assisted by David Pizarro.
90:00 +5:30 Foul by Mauricio Pinilla (Chile).
90:00 +5:30 Egidio Arévalo Rios (Uruguay) wins a free kick in the defensive half.
90:00 +4:20 Offside, Chile. Arturo Vidal tries a through ball, but Alexis Sánchez is caught offside.
90:00 +2:03 Delay over. They are ready to continue.
88:30 Delay in match (Chile) for fighting.
87:29 Dismissal
Dismissal Second yellow card to Jorge Fucile (Uruguay) for a bad foul.
87:25 Alexis Sánchez (Chile) wins a free kick on the right wing. 87:25 Foul by Jorge Fucile (Uruguay).
84:47 Substitution
Substitution Substitution, Uruguay. Jonathan RodrÃguez replaces Carlos Sánchez.
84:33 Substitution
Substitution Substitution, Chile. David Pizarro replaces Jorge ValdÃvia.
83:42 Booking
Booking Mauricio Pinilla (Chile) is shown the yellow card for a bad foul.
83:34 Foul by Mauricio Pinilla (Chile). 83:34 Giménez (Uruguay) wins a free kick in the defensive half.
83:00 Jorge ValdÃvia (Chile) wins a free kick in the attacking half.
83:00 Foul by Egidio Arévalo Rios (Uruguay).
82:17 Gonzalo Jara (Chile) wins a free kick in the defensive half.
82:17 Foul by Abel Hernández (Uruguay).
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